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What Is CBG and What Are the Benefits of This Cannabinoid?

Source: Adrienne Allen/Leafly

By now, most people familiar with cannabis have heard of THC (tetrahydrocannabinol) and CBD (cannabidiol) and their effects, but did you know there are many similar compounds in cannabis? A lesser-known cannabinoid called cannabigerol (CBG), while not present in large quantities in most strains, is nonetheless worth learning about for a number of reasons.

How Is CBG Made?

CBG is a non-intoxicating cannabinoid, meaning it doesn’t produce the “highs” that are synonymous with THC. Because it is present in low levels (usually less than 1%) in most cannabis strains, CBG is considered a minor cannabinoid. Amazingly, however, THC and CBD start out as CBG—it’s the chemical parent of THC and CBD (Figure 1). Cannabis plants produce cannabigerolic acid (CBGA), the precursor to the three main cannabinoid lines: tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), and cannabichromenic acid (CBCA).

Specific enzymes in the plant break CBGA down and “direct” it toward one of the three lines. The acids are exposed to ultraviolet light or heat, and voila, they become the cannabinoids we know: THC and CBD. In most strains, CBGA is immediately converted to either THCA or CBDA. Thus, more THC means less CBG and CBD (and vice versa) by nature of how these compounds are synthesized.

To obtain higher yields of CBG, breeders are experimenting with genetic manipulation and cross-breeding of plants. For example, Subcool Seeds is crossing strains to produce higher CBG contents. Scientists can also extract higher levels of CBG from budding plants by pinpointing the optimum extraction time, about six weeks into an eight week flowering cycle. A medicinal strain called Bediol is produced in this fashion by the Dutch company Bedrocan BV Medicinal Cannabis.

CBG’s Potential Medical Benefits

The human body’s built-in endocannabinoid system (eCS) works to keep the body in its balanced state of homeostasis. While there are specific details about how cannabinoids work, in general the endocannabinoid system performs different functions specific to each area of the body. For example, at an injury site, the eCS can help regulate immune cells to limit inflammation.

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What Is the Endocannabinoid System and What Is Its Role?

CBG has been found to act on very specific physiological systems and problems, and results for medicinal use are promising:

  • Endocannabinoid receptors are prevalent in eye structures, and interestingly, CBG is thought to be particularly effective in treating glaucoma because it reduces intraocular pressure. It is a powerful vasodilator and has neuroprotective effects to boot.

  • In animal experiments involving mice, CBG was found to be effective in decreasing the inflammation characteristic of inflammatory bowel disease.

  • In a recent 2015 study, CBG was shown to protect neurons in mice with Huntington’s disease, which is characterized by nerve cell degeneration in the brain.

  • CBG is showing great promise as a cancer fighter. Specifically, CBG was shown to block receptors that cause cancer cell growth. In one such study, it was shown to inhibit the growth of colorectal cancer cells in mice, thereby slowing colon cancer growth. CBG inhibited tumors and chemically-induced colon carcinogenesis, therefore demonstrating a very exciting possibility for a cure for colorectal cancer.

  • European research shows evidence that CBG is an effective antibacterial agent, particularly against methicillin-resistant Staphylococcus aureus(MRSA) microbial strains resistant to several classes of drugs. Since the 1950s, topical formulations of cannabis have been effective in skin infections, but researchers at the time were unaware of the plant’s chemical composition.

  • In a very recent 2017 study, researchers showed that a form of CBG purified to remove delta-9 THC was a very effective appetite stimulant in rats. This may lead to a novel non-psychotropic therapeutic option for cachexia, the muscle wasting and severe weight loss seen in late stage cancer and other diseases.

  • In a study that looked at the effects of five different cannabinoids on bladder contractions, CBG tested best at inhibiting muscle contractions, so it may be a future tool in preventing bladder dysfunction disorders.

Scientists are excited about these initial CBG results and are promoting future research with CBG alone or CBG in combination with other cannabinoids and therapies for the treatment of multiple maladies. Because it is non-psychotropic, CBG has a promising wide range of potential applications not only for the problems mentioned above, but also as an analgesic, therapy for psoriasis, and as an antidepressant.

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Survey: Nearly Half Of People Who Use Cannabidiol Products Stop Taking Traditional Medicines

Source: Forbes

By Debra Borchardt

The largest survey on cannabidiol or CBD usage to date found that women were more likely than men to use CBD and once they started using it, were likely to drop their traditional medicine. A new survey from Brightfield Group and HelloMD covered 2,400 of HelloMD’s community of 150,000 members and did a deep dive into the usage of CBD products and their effectiveness. HelloMD is an online community that brings together doctors and cannabis patients.

Cannabidiol is a non-psychoactive cannabis compound that doesn’t give users the feeling that they are high or stoned. Instead, it is known to have medicinal qualities. Contrary to the image of men being the predominant consumers of cannabis, this survey found that 55% of the CBD users were women, while men preferred the THC-dominant products. Brightfield Group, which helped conduct the survey, studies consumption patterns and demand trends and is committed to providing accurate data in the cannabis industry which seems to be rife with unsupported claims.

The most common reasons people used CBD were to treat insomnia, depression, anxiety and joint pain, according to Dr. Perry Solomon, the Chief Medical Officer of HelloMD. Forty-two percent of the CBD users said they had stopped using traditional medications like Tylenol pain relievers or prescription drugs like Vicodin and had switched to using cannabis instead. Eighty percent said that they found the products to be “very or extremely effective.” Only 3% or less found the product to be either ineffectual or only slightly effective.

One of the areas that the CBD producers will have to work on is educating the consumer about CBD products. There are more than 850 brands of marijuana-derived CBD products on the market and 150 hemp-derived products. (Marijuana and hemp are the two variations of the cannabis plant.) Eight percent of the consumers surveyed admitted they didn’t know which CBD product they had used.

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What is CBD? What to Know Now about this Cannabis Product

Source: Consumer Reports

Cannabidiol, commonly called CBD, holds the promise of relieving a long list of ailments, from pain to epilepsy to multiple sclerosis. While this chemical compound comes from marijuana or its close relative hemp, CBD does not get users high, unlike another compound from the marijuana plant, tetrahydrocannabinol, or THC.

But because the federal government classifies marijuana as an illegal drug and hemp has a complicated legal status, CBD is also highly controversial.

Still, the CBD market is exploding, expected to multiply sevenfold by 2021, to $2.15 billion from roughly $292 million in 2016, according to the Brightfield Group, a market research firm that specializes in cannabis.

Thousands of CBD products—oils, tinctures, vaporization liquids, pills—are now widely available in stores and online. The World Anti-Doping Agencyremoved CBD from its list of banned substances in January, and some athletes now turn to it for pain relief instead of ibuprofen and related drugs.

Researchers from major educational institutions, including Johns Hopkins and the University of California at San Diego, are studying its potential uses. Some are even examining whether CBD might help in treating opioid addiction.

Meanwhile, 47 states, plus Puerto Rico and Washington, D.C., have passed laws allowing the use of CBD, though with certain caveats, according to NORML, the nation’s oldest marijuana advocacy organization. (See our interactive guide, below.)

But there’s debate about the effectiveness of these products, as well as uncertainty about their legality, especially when they come from hemp. As a result, consumers are left to navigate a confusing marketplace with little guidance about whether the products work, are safe, or even contain the ingredients manufacturers claim.

Two recent events highlighted those issues, offering clarity on some—but not all—questions.

Early last week, the Food and Drug Administration for the first time approveda prescription drug made from marijuana, with CBD as its active ingredient. Called Epidiolex, the drug cut seizures by about 40 percent in people with two rare but devastating forms of epilepsy.

The other news relates to the Senate’s passage of the 2018 Farm Bill. Tucked into its 1,000-plus pages is a provision that makes it easier for farmers to legally grow hemp, something long restricted because of the plant’s association with marijuana. It also includes language that could help clarify the uncertain legal status of CBD that comes from hemp.

Source: NORML (the National Organization for Reform of Marijuana Laws). Data reflects regulations for marijuana. The legality of shipping CBD across state lines is ambiguous. This information is for educational purposes and is not legal advice. Updated as of July 3, 2018.

But whether that will translate into making CBD, at least from hemp, legal across the country is still unknown, says Collen Keahey Lanier, executive director of the Hemp Industries Association, a nonprofit trade group.

One reason: The House and the Senate still need to agree on a final version.

And while the hemp provision appears to have broad support, many Democrats and some Republicans object to other portions of the bill, which could jeopardize its passage.

Another reason: The nation’s long, confused history over all things cannabis suggests that even if the Farm Bill becomes law, it could be awhile before the legal dust settles.

So, is there potential for CBD to treat disease and improve health? Yes, just look at Epidiolex, says Donald Abrams, M.D., a cancer specialist and practitioner of integrative medicine at Zuckerberg San Francisco General Hospital, and a co-author of a report on the medical benefits of cannabis published last year by the National Academies of Science, Engineering, and Medicine.

What Is CBD Anyway?

Cannabidiol comes from one of two related forms of the cannabis plant: marijuana and hemp. The main difference between the two is that marijuana has much more THC than hemp, and often more CBD, too. It’s also harder to extract CBD from hemp than marijuana. But the chemical structure is the same, regardless of the source, say medical and industry experts, so its effect on the body should be the same, too.

Both THC and CBD come mainly from the leaves, resin, or flowering tops of the plants, not the stem. Nearly all products that contain THC also contain CBD. But CBD is often sold and used on its own.

Importantly, hemp oil—found in soaps, cosmetics, and other products—is not the same as CBD oil. Hemp oil comes primarily from seeds of the plant, and the seeds contain only very small amounts of CBD, says Lanier at the Hemp Industries Association.

So hemp oil and other products made from the plant, such as rope and fabric, have no or only trace amounts of both CBD and THC. But hemp cultivation in the U.S. has long been severely restricted by the federal government, making it hard for U.S. companies to make and sell those products. One goal of the new Farm Bill is to loosen those restrictions.

Does CBD Have Health Benefits?

Clearly, CBD can help treat epilepsy, as shown by the recent approval of Epidiolex.

And a growing body of preliminary research suggests that CBD has properties that could translate into better health. For example, CBD seems to be an anti-inflammatory, which in theory could help with arthritis and some forms of pain. And it has many effects on brain chemistry, which could ease anxiety and depression, among others.

One important area: opioid addiction. Some animal studies and early research in humans suggest that CBD may help treat that problem and other forms of substance abuse. And other reports have shown that states with medical marijuana laws have seen drops in the rates of opioid deaths and use, possibly as people turn to cannabis products (which include CBD) as alternatives.

All of that gets researchers excited, says Ryan Vandrey, Ph.D., a Johns Hopkins researcher who is investigating the potential health benefits of CBD, with some promising early findings. But he’s also realistic about the state of the science. “Other than epilepsy, at this point it’s mostly postulation, not proof,” Vandrey says.

And he worries that excessive enthusiasm may be leading people to expect more from CBD than it can deliver. “States are approving CBD to treat conditions based on anecdotal reports and preliminary data,” he says. “I understand that desire, of wanting to help people who think they don’t have any other option. But it may also be false hope.”

Abrams, the cancer specialist who was on the National Academy of Science’s committee on cannabis, agrees. When he and 15 other experts prepared their report, examining more than 10,000 studies in the process, they found only three conditions for which the evidence in humans, not lab animals or other forms of preliminary research, was strong: pain, nausea related to chemotherapy, and spasticity in patients with multiple sclerosis. (The epilepsy studies were published after the NAS report.) And for those conditions, the research wasn’t for CBD in particular but cannabis in general, Abrams says.

For CBD itself, the evidence is even sparser. Abrams says the NAS report could identify only three small published randomized trials—the gold standard for medical research—that looked at just CBD. And for none of those conditions—anxiety, smoking cessation, and Parkinson’s disease—was the evidence strong enough for the NAS report to conclude that CBD clearly helps.

Abrams and Vandrey both blame that lack of definitive evidence not necessarily on the ineffectiveness of cannabis or CBD, but on government rules that for years prevented scientists from using federal money to research the compound’s possible health benefits.

“I’m hoping that now that Epidiolex has been approved, things will open up,” Vandrey says.

And in fact, some restrictions have recently been lifted. Last year, the National Institutes of Health awarded $140 million toward cannabis research, with $15 million going toward CBD studies.  

What About the Safety and Dosing of CBD Products?

With so little research into CBD it’s hard to know for certain how safe it is. That may be particularly concerning for women who are pregnant or breastfeeding.

Still, the research to date has identified few risks. And it appears to be safer than THC, with even the FDA saying CBD poses little risk of abuse. Side effects include tiredness, diarrhea, and changes in appetite and weight.

It’s also unclear what doses or forms of CBD might work best for which conditions, notes Joseph Maroon, M.D., a clinical professor of neurological surgery at the University of Pittsburgh Medical Center who authored a recent review of the neurological benefits of CBD alone and with THC. He writes that with more than 1,000 CBD and cannabis products on the market, in multiple forms, “dosing recommendations are nearly impossible.” And most medical studies have used doses of CBD much higher than that what’s included in products consumers typically purchase, according to ConsumerLab, a company that tests health and beauty products.

In addition, some research suggests CBD may interact with several kinds of prescription meds.

So if you do want to try CBD, talk with your doctor first, especially if you take any prescription drugs or are pregnant or breastfeeding. And until more evidence comes in, be wary of turning to CBD in lieu of more proven therapies, especially for serious health problems like cancer.

Finally, while it’s unclear what dosage might work best for your health problem, it’s still worth looking for products that specifically say they contain CBD, not just “cannabinoids.” Products that say they contain that broader class of compounds may not have much if any CBD. Instead they’re likely to contain other compounds found in cannabis plants, especially the stem. In addition, look for products that list the amount of CBD per serving, not just per bottle.

Is CBD Legal?

Simple question, not so simple answer.

At the state level, CBD from either marijuana or hemp is clearly legal everywhere other than Idaho, Nebraska, and South Dakota. Every other state, plus Puerto Rico and Washington, D.C, has legalized CBD, either alone (18 jurisdictions) or also with THC (31).

Still, details vary from state to state, with many (at least officially) requiring you to get a doctor’s recommendation. And the health problems that states say CBD (alone or with THC) can be used to treat differ, too. For details, see our map.

From a federal perspective, things are less straightforward, depending on whether the CBD comes from hemp or marijuana.

If the source is marijuana, the feds clearly consider it illegal. That’s because the DEA’s position on marijuana is unambiguous: It classifies anything from the plant, including both THC and CBD, as Schedule I substances, meaning that the agency says they have no known medical use and are addictive—just like ecstasy, heroin, and LSD.

Will the FDA’s approval of Epidiolex prompt the DEA to change its position, at least on the “no medical use” clause? Melvin Patterson, spokesman for the U.S. Drug Enforcement Agency, says that’s not certain. Instead, the agency may just reclassify Epidiolex, not all CBD. The agency has 90 days to decide.

The legal questions get more tangled when CBD comes from hemp.

Under its interpretation of the 2014 Farm Bill, the DEA says CBD from hemp is illegal. Unless, that is, the grower raised the plant “under the auspices of a state agricultural pilot program” for research purposes. Or possibly if it comes not from the flower but the stem. Though in that case, if the CBD is an “extracted resin,” it could be illegal again.

Confused? Don’t worry, you’re not the only one.

“As long as there is conflict between federal and state law, there will continue to be confusion over the legal status of CBD,” says Amanda Reiman, Ph.D., a cannabis policy and public health expert based in California who also works for Flow Kana, a cannabis company.

The current Senate version of the Farm Bill tries to unravel the confusion, in part by clarifying that “hemp” means not just the stems of the plant, but seeds, extracts, and all of its cannabinoids—which would include CBD. One important caveat: As in the past, the plant must have THC levels of 0.3 percent or less.

But even if the law does go into effect, it could take time, and possibly lawsuits, to settle the question.  

Can You Legally Buy CBD Online?

Both the DEA’s Patterson and Paul Armentano, deputy director of NORML, the marijuana advocacy group, say they know of no cases where consumers faced legal penalties for buying CBD products online.

But they also say that from a federal perspective, online CBD retailers could be at some legal risk, for several reasons. To start with, shipping CBD across state lines could violate federal law.

For another, those products could violate other government rules, particularly from the FDA. For example, products that claim to treat or cure any disease, ranging from migraine to cancer, run afoul of FDA rules saying that such statement can only be made for approved drugs. In other words, Epidiolex can make those claims, but other CBD products cannot.

And CBD products could still be in violation even if they only make more general claims about health, such as the ability to reduce inflammation or improve immune function. While dietary supplements, such as vitamins and minerals, can say such things, the FDA says CBD products aren’t supplements. Why not? Because CBD has been investigated as a drug—and in fact is now approved as one—and therefore can’t be sold as a supplement.

Since 2015, FDA has in fact cracked down on dozens of online CBD retailers, even threatening to seize products, for precisely those reasons.  

How Can You Know That CBD Products Contain What They Claim?

It’s not easy, though some states do a better job of testing products than others.

The nine states that have legalized both the recreational and medical use of cannabis do require testing of products before they can be sold. Such testing often includes checking for THC and CBD levels, as well as for mold, pesticides, and other contaminants. Some states with only medical cannabis laws also require some testing.  

But among those states, standards vary substantially, with some regulating cannabis products, including CBD-only ones, as if they are pharmaceutical products and others as if they are agricultural ones, says Jennifer Liebreich, at the Association of Public Health Laboratories, which works with states and federal agencies on strengthening laboratory systems and testing programs, including those for cannabis.

Reiman says there may be reasons to be particularly cautious about products ordered online. She notes that there may be less oversight of those products than there is of store-bought ones, making their purity and potency less certain.

Research backs her up. For example, a November 2017 study in JAMA, authored by Vandrey, at Johns Hopkins, found that only 26 of 84 samples of CBD oils, tinctures, and vaporization liquids purchased online contained the amount of CBD claimed on their labels. Eighteen of them had THC levels possibly high enough to result in intoxication or impairment, especially among children. And a quarter had less CBD than advertised. Similarly, FDA testing has found several “CBD” products with no CBD at all.

Consumers need to be “mindful that this is an unregulated industry,” Vandrey says. “So you need to do your due diligence, to make sure what you are buying is what you think it is.”

That may not always be easy, though there are some steps you can take.

For example, look for companies located in states that have legalized the recreational and medical use of cannabis, since they tend to have stricter standards.

Some companies that make CBD products say they also contract with third-party testers to do additional analysis, beyond the state requirements. Kevin Liebrock, chief operating officer at Bluebird Botanicals in Louisville, Colo., says that’s what his company does. And, he says that they post the results online, so customers can check to see that they are “getting the advertised amounts of cannabinoids, like CBD, and that the product is free of contaminants.”

Other companies, such as Floyd’s of Leadville, also post their results online. And Maggie Frank, national educator at CV Sciences, maker of PlusCBD Oil, says customers should ask to see the Certificate of Analysis, or COAs, which show the results of those tests. If a company won’t do that, she says, “that’s a red flag.”

Can I Legally Fly With CBD Products?

Many people do, but that doesn’t mean you can or should, says Armentano, at NORML. That’s because the same concerns about buying it online apply to flying with it. After all, you’re probably crossing state lines.

The U.S. Transportation Safety Administration says that while its agents don’t specifically search for cannabis products, if they find any—including CBD-only ones—they are supposed to refer you to law enforcement.

Even if that doesn’t lead to legal action, it could delay your travel and possibly even hamper future trips through TSA security or jeopardize your ability to qualify for TSA PreCheck.  

Reporting by Lisa Gill and Lea Ceasrine. 

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CBD vs. CBDa

CBD vs. CBDa: What’s the Difference?

Source: Daintri

Cannabidiol (CBD), the popular non-psychoactive component of the cannabis plant, has been gaining a lot of attention in recent years due to its tremendous therapeutic properties. Studies have proven that this chemical compound can have a significant positive impact on many functions of the human body including immunity, metabolism, mood, appetite, sleep, pain tolerance, and mental competence. It is the second-most prominent cannabinoid found in the cannabis plant (after its contrasting psychoactive component, THC), but what you may not know is that it exists as cannabidiolic acid (CBDa) first before it is processed and used for medical and health purposes – only then officially being labeled at CBD after undergoing degradation or decarboxylation (heating of raw cannabis).

With CBD becoming the most promising cannabinoid for medical research, CBDa has been overlooked in the past. Although, a new trend of juicing raw cannabis has brought CBDa back into the spotlight. Since CBD is derived from CBDa, there is a common misconception that they are the same chemical compound. In actuality, they differ from each other in a number of ways including chemical composition, working mechanism and health benefits.

If they are in fact two different chemical compounds, how does CBDa become CBD?

First, let us explain exactly what CBDa is, then what CBD is, as their own separate elements.

Found in fresh cannabis plants, CBDa is the acidic precursor to CBD. While it has some healing properties of its own, it is often processed so that it can provide more health benefits. CBDa will naturally become CBD as it undergoes degradation over time, but it can be transformed more quickly through decarboxylation. While this process of decarboxylation may sound complex, it is actually the simple act of heating cannabis materials, either through cooking, vaporizing or smoking. Depending on the amount of time or heat applied, decarboxylation may or may not completely turn CBDa into CBD. This means that the resultant chemical compound may still contain a trace amount of CBDa.

Differences Between CBDa and CBD

Chemical Composition

The chemical formulas for CBD and CBDa are C₂₁H₃₀O₂ and C₂₂H₃₀O₄ respectively. The former has a simpler chemical composition because of the absence of a carboxylic acid group, which is removed through decarboxylation. The removal of the carboxyl group turns the inactive components in CBDa into active components, thereby unlocking more therapeutic properties.

Working Mechanism

  • CBD and CBDa both have a positive impact on the body’s endocannabinoid system (ECS), which serves to regulate balance in immune response, cellular communication, metabolism, mood, and other bodily functions. While they do not interact directly with the main receptors of the ECS, they can both activate and inhibit other receptors to keep the body healthy.
  • In terms of “working mechanisms,” the main difference between CBD and CBDa lies in the types of receptors they influence:
    • CBD is known to react with adenosine, serotonin and vanilloid receptors to mediate pain, inflammation, anxiety, depression and other conditions.
    • CBD also inhibits the CPR55 receptor to improve bone density, blood pressure, and cancer-fighting abilities.
    • CBDa, on the other hand, works by blocking the activities of receptors responsible for causing inflammation, such as COX-1 and COX-2. By doing so, CBDa can reduce seizures, inflammation, and symptoms of diseases.

Researchers have found that CBD and CBDa provide the best results when they work together. This is especially true if the condition results from the improper regulation of multiple systems in the body. Recent studies showed that CBDa can also enhance the potency of CBD, allowing users to use a smaller amount to attain the same level of effectiveness.

Health benefits of CBD and CBDa

Both CBD and CBDa are suitable for healthcare use because they are non-psychoactive, meaning they do not make their users feel “high.” While they have several similar health benefits, these compounds are not entirely the same in terms of therapeutic effects. The process of decarboxylation activates certain dormant medicinal properties of CBDa, but it also results in the loss of beneficial cannabis oils called terpenes. Therefore, CBD does provide a wider range of health benefits but it does not offer as many terpene-related benefits as CBDa.

To date, CBD has been more extensively studied than CBDa. Researchers have found that CBD can help improve the general well-being of an individual, and is said to alleviate many health problems, including:

  • Inflammation
  • Pain
  • Loss of appetite
  • Nausea
  • Sleeping Difficulty
  • Anxiety
  • Depression
  • Epilepsy
  • Diabetes
  • Heart Disease
  • Stroke
  • Cancer
  • Multiple Sclerosis
  • Alzheimer’s Disease
  • Parkinson’s Disease
  • Acne
  • Addiction

Compared to its active counterpart, CBDa has gotten significantly less attention from research. As such, CBDa’s true potential is relatively unknown. However, experts have so far discovered that it can help treat a number of health conditions (some of them the same as CBD’s), including:

  • Bacterial Infection
  • Pain
  • Inflammation
  • Nausea and Vomiting
  • Seizure
  • Arthritis
  • Cancer
  • Anxiety
  • Psychotic Disorders

Despite their differences, both CBD and CBDa can be extremely beneficial to anyone’s health. Whether you wish to use these powerful compounds to treat a specific condition or to improve general health, it is important that you select products that are effective and safe.

Conclusion

CBDa is found in fresh, whole plant (or raw) cannabis. Over time, the substance breaks down through decarboxylation, transforming into CBD. It does this by removing the acid group of the molecule. CBDa is the parent molecule of CBD. Both CBD and CBDa have unique health benefits that keep the endocannabinoid system operating smoothly. For example, CBDa may not be as effective as CBD for inhibiting breast cancer cell proliferation, but it is more effective than CBD as a nausea and vomiting treatment.

TAKEAWAYS

  • CBD is a substance with a curative effect that can be used for a variety of complaints
  • CBDa is a strong variant of CBD containing a heightened value which results in a strengthened effect
  • CBD and CBDa are beneficial compounds both by themselves and when working together
  • CBD and CBDa contain no psychoactive substances, and therefore have no mind-altering effects
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Seven Types of People That Can Benefit from CBD

1. Children with Epilepsy 

Epilepsy or ‘Dravet Syndrome’ is a neurological disorder marked by sudden recurrent episodes of sensory disturbance, loss of consciousness, or convulsions, associated with abnormal electrical activity in the brain. It’s a condition that averages about 200,000 cases per year between adults as well as children. Family members all over the world are suffering from between 1 and 300 seizers daily from this extreme condition, and pharmaceutical drugs do not seem to be solving the problem. 

Cannabidiol (CBD) extracts and oils are saving children with Dravet’s, showing massive reduction in the number of daily seizures. Reference the video below for an incredible story of two young children with Dravet’s, and how CBD changed their quality of life.

From 300 seizures a week, Charlotte is now down to zero to one per week. It’s incredible.

— Charlotte’s Mother

2. Veterans

“The mission of Warfighter Hemp is to provide our nation’s veterans with an organic, non-addictive, non-psychoactive means to manage pain, lower anxiety, and improve the overall quality of their lives. Warfighter Hemp believes that our 23 million Veterans can lead the way in demonstrating that there is a viable alternative to the over prescription of addictive medications and offer a pathway out of the opioid epidemic currently plaguing our society.” – https://www.warfighterhemp.com/ 

 

3. Senior Citizens  

“Many seniors are not aware of how medical cannabis could improve their quality of life and how the stereotypical marijuana user and use has changed. Because CBD is extracted from the marijuana plant, seniors can take advantage of the medical benefits afforded by the extract without the head or body sensation often associated with marijuana. Additionally, seniors have the option of delivering CBD to their bodies in forms more familiar, rather than inhaling smoke. CBD is an oil extract and therefore can be added to things like topical gels, tinctures and edible products.

In many cases, these derivatives of cannabis can reduce or even replace the use of harmful and addictive prescription drugs. While this information is only now making its way into the mainstream, the natural consequence is, seniors drop their prejudices, face the reality and turn to the treatment of their minor and major age-related diseases using cannabis.” – https://seniordirectory.com/articles/info/benefits-of-cbd-for-senior-citizens

 

4. Athletes

CBD Helps With Inflammation

One of the biggest issues athletes face on a daily basis is inflammation. CBD oil acts as an anti-inflammatory which is a great way to prevent joint injury during physical activity, as well as reduce any pain from swelling. CBD topical creams are a great alternative to things like lidocaine or bengay.

Pain Relief

While OTC painkillers are proven to mask most pain completely, they can put you in a fog, as well as give you a false sense of ability when you are injured or in pain. CBD is a much clearer way to combat the pain, and won’t put your brain into a fog.

Reduce Game-Day Stress and Anxiety

Sometimes no matter how long and hard we train, we still get a little nervous before a big game or event. One of the best benefits that you can get from CBD oil is some relief from performance anxiety.

CBD is notorious for its anti-depressant/anxiolytic properties, many patients with anxiety disorders or depressive disorders have turned away from harmful and habit-forming anti-depressants like Zoloft, Xanax, and Prozac and turned to the non-habit forming and all natural CBD oil.

Faster Recovery Time

Sometimes hurting yourself is just inevitable. Instead of turning to OTC painkillers like Vicodin, Percoset, or Methadone, which only help with pain, you can combat pain as well as speed up your recovery time with CBD products.

Not sold on the healing properties of CBD yet? Keep this in mind: CBD has been proven to treat and heal all sorts of medical diagnoses, from seizures to degenerative diseases like Multiple Sclerosis, and even has treated and cured different forms of cancer. If it can heal you from disease, it can and will heal you from any injury that you sustain.

CBD is truly the healing cannabinoid, and it will help you get back into the game much faster than any OTC medication will. Not to mention, it is all natural and from the earth, rather than concocted in a lab.

CBD Oil and Head Injuries

New research has recently surfaced regarding CBD and it’s medicinal benefit to head injuries. In a three-year study, researchers found that out of 446 patients who had suffered from Traumatic Brain Injury (TBI) about 97% of those who had previously used cannabis prior to the event survived the TBI.

Comparatively, 88% of those patients who did not previously use cannabis survived the TBI. There is also evidence that proves that using cannabis products such as CBD oil not only helps treat brain injury, but it actually helps protect the brain from suffering an injury at all.

For athletes that are subject to hits and blows to the head such as football players, hockey players, and gymnasts, CBD oil could mean the difference between a severe concussion, and just a foggy head for a while.

CBD is Great For Your Immune System

There is nothing worse than training and practicing for an event for months or even years, and then right before it’s time to perform or the big game is about to start, you get sick. CBD oil will help you with that because it boosts your immune system.

Not only will the be helpful for the big game or event, it will also help you stay healthy while your training, especially during the winter months where you are more likely to get ill. The reason for this is because CBD is high in antioxidants, which helps lower your risk for infection, and is also great for your heart health.

It Can Help You Control Your Appetite and Weight

CBD works great for curbing your appetite and helping you take control of your weight. As an athlete, half of the battle is putting the best foods into your body to increase your longevity and performance. If you are struggling to stick to that specific diet, or want to cut a healthy amount of weight before an event, CBD products can help.

This is surprising to many, as marijuana and cannabis products are typically associated with excessive eating or the “munchies.” That craving to eat is actually only associated with the THC in weed. CBD doesn’t give you that and has actually been proven to do the opposite.

Not only does it slow your appetite, it also keeps you feeling full for longer, which is great for that diet you’ve been trying to help you get ready for a big event. It has also been found to improve insulin function, which is also a contributor to feeling great after you eat, and not overeating.

So What Are You Waiting For?

CBD is taking the athletic industry by storm with all of these new studies and findings proving exponential medicinal value. We offer many different types and potencies of CBD oil that are perfect for any athlete.

With this completely legal, inexpensive, and all natural alternative to modern medicine, we only have one question for you is “What are you waiting for?” – https://floydsofleadville.com/benefits-cbd-oil-athletes/

5. People Living with Depression 

Depression is a pathology that affects many people in many aspects of life, including social life, productivity, and overall wellness. As we learn more and more about Cannabidiol (CBD), we learn how it can help play a positive effect on the psychological aspect of a persons life. Using CBD as a natural alternative has become increasingly popular amongst people living with severe depression, and just about everyone that has tried CBD, found CBD to be more beneficial than anti-depressants. 

6. People Living with Anxiety 

Anxiety is a feeling of worry, nervousness, or unease, typically about an imminent event or something with an uncertain outcome. Anxiety disorders are the most common mental illness in the U.S., affecting 40 million adults in the United States age 18 and older, or 18.1% of the population every year. t’s not uncommon for someone with an anxiety disorder to also suffer from depression or vice versa. Nearly one-half of those diagnosed with depression are also diagnosed with an anxiety disorder. 

A small 2010 study found that cannabidiol could reduce symptoms of social anxiety in people with social anxiety disorder (SAD). Brain scans of participants revealed changes in blood flow to the regions of the brain linked to feelings of anxiety.

In this study, cannabidiol not only made participants feel better but also changed the way their brains responded to anxiety.

A 2011 study also found that cannabidiol could reduce social anxiety. For that study, researchers looked specifically at cannabidiol to treat anxiety associated with public speaking.

Research published in 2014 found that CBD oil had anti-anxiety and antidepressant effects in an animal model.

A 2015 analysis of previous studies concluded that CBD oil is a promising treatment for numerous forms of anxiety, including social anxiety disorder, panic disorder, obsessive-compulsive disorder, generalized anxiety disorder, and post-traumatic stress disorder

 

7. The Everyday Person

If we are being honest, just about everyone in the world can reap the benefits of CBD products. Whether you live an active lifestyle, want to focus more, care about your health & well-being, or get the occasional headache, CBD can help play a positive roll in your life (or someone very close to you).

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Why Retail Locations Need Quality Hemp Derived Products

Have a retail brand? Be a part of this revolution, and see the benefits of selling CBD!

1. Natural, Safe, Alternative Remedies 

Cannabidiol (CBD) is a non-psychoactive compound found in the cannabis plant and is found to have incredible medicinal applications. Helping with ailments such as soreness and migraines to epilepsy and schizophrenia, consumers all across the nation are finding out about the potential benefits of CBD and how they can integrate CBD into their lifestyle.

2. Incredibly High Demand Across the U.S

America is in the midst of a ‘Green Rush’ with the  legalization of Medical Marijuana in multiple States. The market has incredible momentum and it will be tough for the Government to stop it now. With the Farm Bill being passed in 2014, thousands of people are looking to get their hands on quality, organic industrial hemp derived products.

Industrial hemp is non-psychoactive with little to no THC levels, and has genetically distinct varieties of the plant, Cannabis sativa. Hemp has absolutely no use as a recreational drug. Section 7606 of the Farm Bill defines industrial hemp as “the plant Cannabis sativa L. and any part of such plant, whether growing or not, with a delta-9 tetrahydrocannabinol concentration of not more than 0.3 percent on a dry weight basis.” This makes hemp derived products containing less than 0.3% THC levels, legal to sell in all 50 states. This suddenly opens up a massive market for consumers looking to improve their overall health and wellness.

3. Custom Formulations

Do you formulate your own products?Are you a CBD artisan? Then you know that there are very diverse applications for CBD Isolate and oils. Bring us your custom formulation, or use one of ours, we can help you cary bulk finished products via white label or private label services.

5. It’s 100% Legal to Sell in ALL 50 States!

Whether your store is in Colorado, Kansas, Florida, or New York, you are aloud to cary and sell CBD products. We make sure you have a qualifying re-sellers license, and all of our products contain zero THC. We stay up to date with current rules & regulations to make sure our network is following the law.